There is some data that suggests when people experiment with alcohol in their youth, this predisposes them to a long list of harmful effects later in life, addiction included. This provides yet another reason why parents should do everything they can to prevent their children from experimenting with alcohol.
Historically, alcohol misuse has affected men far more than women. Today, while alcohol abuse still affects more men than it does women, the gap is closing, and women are becoming increasingly afflicted with alcohol addiction.
Alcohol is unique in that, while it is most definitely a mind-altering substance, its use is also quite normalized in day-to-day life. Where do you draw the line? How do you know what qualifies as alcohol use and what qualifies as misuse?